The CBR900RR was introduced in 1992 and was fitted with an 893 cc (54.5 cu in) inline-four engine. When introduced, it set a precedent for light weight in the super bike class. At 453 lb (205 kg) with a full tank of gas, the CBR900RR was just 4 lb (2 kg) heavier than Honda's own CBR600F2, and 76 lb (34 kg) lighter than the next-lightest open-class machine at the time, the Yamaha FZR1000. Minor changes to the 1994 model included an improved shift drum to cure notchy shifting, and steadier mirrors.

In a move to refine the CBR900RR's handling traits on bumpy roads, the 1995 model's suspension was upgraded with revised spring and damping rates, and a compression adjuster was added to the front fork. More aggressive bodywork incorporated a "cut reflector" design headlight and fewer of the CBR's unique fairing holes. Slimmer and firmer footpegs were patterned after the RC45 and a shift linkage replaced the original model's backward pedal. A new instrument panel included an electronic speedometer that measured speed from the countershaft sprocket. The only engine change in 1995 was the replacement of the aluminum valve cover with a magnesium piece.